Increasing awareness
of hereditary
angioedema (HAE)

The Hereditary Angioedema Awareness kit is designed to promote an understanding of HAE among peers, family members and others who are unfamiliar with the condition.


Learning about hereditary angioedema (HAE) is an essential part of living with the condition.That’s why it’s so important for friends and family members of those diagnosed with HAE to have a true understanding of the condition. Although it is an inherited disorder, family members often go untested.

Because the symptoms of HAE often mimic those of other diseases, misdiagnosis is common. Spreading awareness can help ensure that those with the condition receive an accurate--and early--diagnosis. It can also help friends and family of those who have the condition to recognize symptoms as well as understand and avoid potential attack triggers.

A helpful solution for supporting HAE patients

With the Patient Service Center (PSC), available through the CINRYZESolutions® Programs, patients who have been prescribed CINRYZE® (C1 esterase inhibitor [human]) can work with a Patient Care Coordinator (PCC) to simplify and facilitate insurance authorizations, financial assistance, and other matters related to CINRYZE therapy.

To learn more about what the CINRYZESolutions Programs can do for you, be sure to speak with a PCC at 1-877-945-1000 or send an email to

If you have not been prescribed CINRYZE, visit for resources and information about hereditary angioedema and CINRYZE.

CINRYZE® (C1 esterase inhibitor [human]) is an injectable medicine that is used to help prevent swelling and/or painful attacks in teenagers and adults with Hereditary Angioedema (HAE).
Important Risk Information
You should not use CINRYZE if you have had life-threatening immediate hypersensitivity reactions, including anaphylaxis to the product.

Tell your healthcare provider about all of your medical conditions, including if you:
  • have an indwelling catheter/access device in one of your veins.
  • have a history of blood clots, heart disease, or stroke.
  • are taking birth control pills or androgens.
  • are pregnant or planning to become pregnant. It is not known if CINRYZE can harm your unborn baby.
  • are breastfeeding or plan to breastfeed. It is not known if CINRYZE passes into your milk and if it can harm your baby.
Tell your healthcare provider and pharmacist about all of the medicines you take, including all prescription and non-prescription medicines such as over-the-counter medicines, supplements, or herbal remedies.

Allergic reactions may occur with CINRYZE. Call your healthcare provider or get emergency support services right away if you have any of the following symptoms:
  • wheezing
  • difficulty breathing
  • chest tightness
  • turning blue (look at lips and gums)
  • fast heartbeat
  • swelling of the face
  • faintness
  • rash
  • hives
Because CINRYZE is made from human blood, it may carry a risk of transmitting infectious agents, e.g., viruses and, theoretically, the Creutzfeldt-Jakob disease (CJD) agent.

The most common side effects seen with CINRYZE were headache, nausea, rash, and vomiting. These are not all the possible side effects of CINRYZE. Tell your healthcare provider about any side effect that bothers you or that does not go away. You can also report side effects to ViroPharma Medical Information at (866) 331-5637 or the FDA at 1-800-FDA-1088.

Medicines are sometimes prescribed for purposes other than those listed here. Do not use CINRYZE for a condition for which it is not prescribed. Do not share CINRYZE with other people, even if they have the same symptoms that you have.

Before starting CINRYZE, please read the accompanying Patient Information carefully and each time you get a refill. This information does not take the place of talking with your healthcare provider, and it does not include all of the important information about CINRYZE. If you have questions after reading this, ask your healthcare provider.

Please see the accompanying Full Prescribing Information.

©2010-2013 ViroPharma Incorporated. All rights reserved. CINRYZE, RYZE ABOVE, CINRYZESolutions, CINRYZEConnect and associated logos are either trademarks or registered trademarks of ViroPharma Biologics, Inc. VIROPHARMA and the ViroPharma logo are trademarks of ViroPharma Incorporated.